Blood rheology in men with essential hypertension and capillary rarefaction

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Treatment of Essential Hypertension does not Normalize Capillary Rarefaction

OBJECTIVES To determine if capillary rarefaction persists when hypertension is treated with angiotensin converting enzyme inhibitor, thiazidic diuretic and/or beta-blocker, and to identify which microcirculatory alterations (structural and functional) persist after anti-hypertensive treatment. METHODS We evaluated 28 well-controlled essential hypertensive patients and 19 normotensive subjects...

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Impaired skin capillary recruitment in essential hypertension is caused by both functional and structural capillary rarefaction.

Capillary rarefaction occurs in many tissues in patients with essential hypertension and may contribute to an increased vascular resistance and impaired muscle metabolism. Rarefaction may be caused by a structural (anatomic) absence of capillaries, functional nonperfusion, or both. The aim of this study was to assess the extent of structural versus functional capillary rarefaction in the skin o...

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ژورنال

عنوان ژورنال: Journal of Human Hypertension

سال: 2002

ISSN: 0950-9240,1476-5527

DOI: 10.1038/sj.jhh.1001454